Article: A coding variant in TMC8 (EVER2) is associated with high risk HPV infection and head and neck cancer risk.
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Liang C; Kelsey KT; McClean MD; Christensen BC; Marsit CJ; Karagas MR; Waterboer T; Pawlita M; Nelson HH
PLoS ONE, 2015
10.1371/journal.pone.0123716.t001
Demographic characteristics of cases and controls.
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| Characteristic |
Cases (n = 361) |
Controls (n = 414) |
P |
| Age (years) |
59.7 ± 11.5 |
61.0 ± 11.6 |
0.11 |
| Gender |
|
|
0.77 |
| Female |
94 (26%) |
103 (24.9%) |
|
| Male |
267 (74%) |
311 (75.1%) |
|
| Pack-years of tobacco use |
|
|
<0.0001 |
| Never |
62 (17.2%) |
137 (33.1%) |
|
| 0 to <20 |
60 (16.7%) |
116 (28.0%) |
|
| > = 20 |
239 (66.2%) |
161 (38.9%) |
|
| Alcohol consumption, average drinks per week |
|
|
<0.0001 |
| <8 |
122 (37.9%) |
239 (58.0%) |
|
| > = 8 |
200 (62.1%) |
173 (42.0%) |
|
| Missing |
39 |
2 |
|
| HPV L1 serology Positive:Negative (%) |
|
|
|
| HPV16 |
70:291 (19%) |
14:400 (3.4%) |
<0.0001 |
| HPV18 |
43:318 (12%) |
30:384 (7.2%) |
<0.04 |
| HPV11 |
35:326 (9.7%) |
17:397 (4.1%) |
<0.003 |
| HPV31 |
37:324 (10.2%) |
22:392 (5.3%) |
<0.01 |
| HPV33 |
15:346 (4.2%) |
9:405 (2.2%) |
<0.17 |
| HPV35 |
33:328 (9.1%) |
14:400 (3.3%) |
<0.001 |
| HPV45 |
18:343 (5.0%) |
12:402 (2.9%) |
<0.19 |
| HPV52 |
19:342 (5.3%) |
3:411 (0.7%) |
<0.0003 |
| HPV58 |
20:341 (5.5%) |
6:408 (1.4%) |
<0.003 |
| Tumor sites |
|
|
|
| Oral |
148 (41.0%) |
|
|
| Pharynx |
148 (41.0%) |
|
|
| Larynx |
65 (18.0%) |
|
|
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |
